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A Simple Genome Annotator?

A question to genome annotators out there. I need a simple genome annotator for annotating bacteriophage genomes in an undergraduate course. Until now, we used DNAMaster but for various reasons  I would like to move away from that. Here’s what  I need for class: 1. Annotate a single assembled linear chromosome, about 50,000 bp, 80-120 genes, no […]

A bit more on writing bioinformatic research code

There has been a lot of discussion recently on this blog and others on the need for robust scientific software. Most of the discussion I have been involved in comes from bioinformaticians, because, well, I am one. There has been plenty of talk about code robustness, sharing, and replicability vs. reproduciblity. I do not want […]

Reproducible research software: some more thoughts

So there was a lot written over the blogosphere, twittersphere and what-have-you-sphere about the to publish code in scientific research. The latest volley was fired from a post at biostars.org from “JermDemo” which also mentioned my post on making accountable research software by forming a volunteer “Bioinformatics Testing Consortium”. (My post, not my idea). I won’t […]

DIGging into Images and Genomes

Our lab has a new project and website up. The project is BioDIG: Biological Database of Images and Genomes.  BioDIG lets you combine image data and genome data of, well, just about anything which you can make images and have a genome, or partial genomic information. You can upload your image, annotate (tag) parts of […]

Operating systems and sandwiches

Ubuntu Linux: “You can have your sandwich any way you like, but recently we started wrapping it in this really ugly wrapper. Still yummy though, and you can ask for a different wrapper. But you have to ask”. Mac OSX: “We only serve ham & cheese on white bread. If you don’t like it, go […]

Bio-Linux. Now available in the Cloud

For some time now, NERC has been providing us with Bio-Linux. If you don’t want to be bothered with installing all the essential bioinformatic software for your Ubuntu box, you can install Bio-Linux, either as a a Linux distro for installation from scratch, or as a set of packages for an already existing Debian or Ubuntu […]

Closing gaps

Geek alert: this post for coders. So you sequenced your genome, reached an optimally small number of contigs, they look sane, and now you would like to see what you need for the finishing stage. Namely, how many gaps you have and what are their sizes. UPDATE: “might just be worth clarifying this is for […]

Android apps for scientists

A few science apps for the Android mobile phone operating system. Some of these I have, some I don’t , and some I really would like to check out. Feel free to add more that you know of in the comment section. Better yet, make a wish… Science Literature: AgileMedSearch: Searching through pubmed databases. Pretty […]

Absolut standards: report from the M3-2009 meeting, part 2: signature genes and big science

Some more presentations from the metagenomics, metadata, and metaanalysis (M3) meeting, Stockholm June 27, 2009 Pathway Signature Genes Lucas A. Brouwers, Martijn A. Huynen and Bas E. Dutilh CMBI / NCMLS, Radboud University Nijmegen Medical Centre, The Netherlands If we take a sample of soil, how can we know whether it is adequate for growing […]

Test driving the Wolfram Alpha

There has been a lot of buzz recently about Wolfram’s new product, the Wolfram Alpha (WA). After attending a webinar on WA, I was given a preview account, and started messing around with it.  In case you were wondering, that is the extent of my involvement with Wolfram Research, LLC, I don’t even have a […]