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Microbiology

I’m Moving and Hiring

Starting June 1, 2015, my lab is moving to Iowa State University in Ames, Iowa, and I’m very excited about this. I’ll be joining a growing cohort of researchers as part of a presidential “big data” hire the university has started a year ago. The research environment is superb, and there are some great bioinformaticians and genomics […]

Friday bits and pieces: ebola, old software patches, microscopy and microbiomes

  Scammers are cashing in on the ebola scare. The news media is cashing in on the ebola scare. Politicians are cashing in on the ebola scare. Unfortunately, neither international healthcare nor biomedical research  are cashing in on the ebola scare.   I found the first software patch. Seems pretty robust.   Diet can influence certain autoimmune […]

Quit smoking, more bacteria will like you

As an ex-smoker I can attest to this: quitting is  hard.  It can also make you fat. I gained quite a few kilos when I quit, and those took a long time to lose. Happily, these days I am spending money on running marathons rather than on cigarettes. Weight gain after smoking cessation is fairly […]

New Links between Bacteria and Cancer

Microbiology and Cancer Cancer and microbiology have been closely linked for over 100 years. Cancer patients are usually immunosuppressed due to chemotherapy, requiring special treatment and conditions to prevent bacterial infection. Bladder cancer is typically treated with inactivated tuberculosis bacteria to induce an inflammatory response which turns against remaining cancer cells, with remarkably effective results.  Also, viruses are […]

The power of single-cell genomics: the mysterious SR1 bacteria have a unique genetic code

Thanks to Mitch Balish for calling my attention to this one. SR1 bacteria are not exactly a household name, even among microbiologists. They were first discovered in contaminated aquifers,  and since then they were found to be also in animal and insect guts, as well as in human mouths. They are even suspected of being […]

The Black Queen Hypothesis

“Well, in our country,” said Alice, still panting a little, “you’d generally get to somewhere else — if you run very fast for a long time, as we’ve been doing.” “A slow sort of country!” said the Queen. “Now, here, you see, it takes all the running you can do, to keep in the same […]

Life Stands on the shoulders of Giants (Viruses)

Back to ancient life, what exactly defines life, and where does life end and non-life begin. One of my favorite subjects, and one of which I am the least knowledgeable. Doesn’t stop me writing about it though. Viruses are… well… not really life. Or so says common wisdom. They have some elements of life: a […]

Not “Ancient”. Still Cool.

 This commentary appeared in Nature  recently. Title:  Ancient Fungi Found in Deep Sea Mud. Quote: Researchers have found evidence of fungi thriving far below the floor of the Pacific Ocean, in nutrient-starved sediments more than 100 million years old….To follow up on earlier reports of deep-sea fungi, Reese and her colleagues studied sediments pulled up from […]

Our Home’s Wild Life

  Today Nitzan & I were citizen-scientists, sampling several locations in our home for microbial sequencing. We did this as part of Your Wild Life, a project hosted at North Carolina State University’s Biology Department. The Wild Life of Our Homes looks to sequence household microbial communities in a large number of homes. From their […]

Repost: the New Natural History

Today is the last day of the 19th Lake Arrowhead Microbial Genomics meeting. A great meeting of everything good: science, atmosphere, people and location. Good tweeter coverage too, at #LAMG12 The many genomic characterization talks in the meeting reminded me of a post I wrote three years ago. I decided to repost it, and dedicate […]

ISMB 2012 Vignettes Pt. 3: Swag

Promotional materials are part of any conference. In scientific meetings, the swag usually comes from the booths of product promoters, science publishers, and scientific societies. It was a nice surprise to see a Federal funding agency, the US Department of Energy give away decks of cards. I’m a sucker for cards, so I took a […]

ISMB 2012 Vignettes Pt. 2: Phylogenomic Approaches to Function Prediction

I chaired the Automated Function Prediction meeting at ISMB this year. The meeting, held every year (almost) deals with the latest approaches to predicting protein function from genetic and genomic data, and also discussing the Critical Assessment of Function Annotation This year we were fortunate to have Jonathan Eisen as our keynote speaker. Ever wondered […]

Intermission: two vids

Too busy with grant deadlines, and preparations for the looming ISMB 2012. (Including, of course, the Automated Function Prediction meeting.) So here are two nice vids to pass the time. Jennifer Gardy and Tom Scott made this great A-Z of bacteria video.  Guaranteed to freak out your kids, or yourself. So how many of those […]

Phound phage phootage

I am finishing up a great weekend at HHMI Janelia Farm Research Campus. The occasion is an annual symposium celebrating the Phage genomics Course taking place in dozens of universities in the USA. Here are two of our students, Erich Goebel and Morgan Light, next to the poster they presented at the meeting: This post […]

Repost: Shavuot is a Microbial Holiday

Yesterday was Shavuot. That wonderful holiday which includes midnight studies, water-bombing and dairy products. Mmmmm…. cheese. A food product heavily embedded in the science of microbiology. Cheese is the founding product of the biotech industry (along with beer and bread). So here’s to Lactobacilli and Lactococci which are at the center of the production of […]