Displaying posts tagged with

“genome annotation”

A Simple Genome Annotator?

A question to genome annotators out there. I need a simple genome annotator for annotating bacteriophage genomes in an undergraduate course. Until now, we used DNAMaster but for various reasons  I would like to move away from that. Here’s what  I need for class: 1. Annotate a single assembled linear chromosome, about 50,000 bp, 80-120 genes, no […]

Job opening: Scientific Curator at the Jackson Laboratory

Scientific Curator – Bioinformatics Interested individuals should apply on-line at www.jax.org/careers, referring to job posting #3256.  Contact Jeannine Ross at ext. 6045 with questions. The incumbent in this position plays a critical role in data annotation and curation for the Gene Ontology (GO) and Protein Ontology (PRO) programs at The Jackson Laboratory in Bar Harbor […]

Gene and protein annotation: it’s worse than you thought

Sequencing centers keep pumping large amounts of sequence data into the omics-sphere (will I get a New Worst omics Word Award for this?)  There is no way we can annotate even a small fraction of those experimentally and indeed most  annotations are automatic, done bioinformatically. Typically function is inferred by homology: if the protein sequence […]

The Human Genome Variome Project and Google News Reader

Apparently sequencing two white males of European extraction does not make for a very good sample of mankind, and that if we really want to get a good view of what we are really like, we need to sequence a couple more. Maybe even, you know, a woman, or someone from India or China or […]

My own post genomic moment

Maybe I am slow on the uptake, but I never quite liked the term “post genomic”, and I used it very sparingly. (Yes, I do have that term in one of my better cited papers, smack in the first sentence of the abstract, but I never liked that).  Perhaps because of all the associated abuse […]