The Friedberg Lab is recruiting graduate students, for both Master’s and Ph.D. WE ARE: A dynamic young lab interested in gene, gene cluster and genome evolution, understanding microbial communities and microbe-host interactions by metagenomic analyses, developing algorithms for understanding gene cluster evolution, and prediction of protein function from protein sequence and structure. YOU ARE: [...]
Hats off to Jonathan Eisen for hosting this activity on his blog. (I’ll keep mine on, thank you. It’s raining cats and dogs here right now). A couple of weeks ago I posted a discussion about two papers that challenged the ortholog conjecture. Briefly, both papers stated that orthologs may not be such great [...]
I have posted quite a few times before about the acquisition of new functions by genes. In many cases a gene is duplicated, and one of the duplicates acquires a new function. This is one basic evolutionary mechanism of acquiring new functions. Sometimes, gene duplication occurs within a species: part of the chromosome may be [...]
I am fascinated with zombies. Always have been, but even more so since I took an interest in microbiology. The zombie apocalypse is the best known and best chronicled viral infection which hasn’t happened. But it could happen any day, so stock up on non-perishable food, medical supplies, water purification tablets, chainsaws, machetes, baseball [...]
OK, I think the tree of life is obsolete. I have been spending a lot of time looking at horizontal gene transfer, reading about it, looking at it in genomes until my eyes water and my brain dessicates, occasionally blogging about it and soon to be publishing about it. Life is not a tree. [...]
William Shakespeare was baptized April 26, 1564. His birthday is traditionally commemorated on April 23 (incidentally, that is also the date of his death, in 1616). One interesting connection between Shakespeare and evolution was made by Richard Dawkins in his book The Blind Watchmaker: I am talking about the Weasel program. Weasel is an elegant illustration of the [...]
Some microbes are evil minions of Hell (but not all) Quite a few people think that microbes are evil, disease causing minions of Hell that should be eradicated. Supermarkets are handing out sanitary wipes: wipe the handlebar if you want to live, never mind that 90% of the food in the supermarket is worse for [...]
I have just returned from British Columbia in Canada. I have to admit that their license plate motto is quite accurate: BC is incredibly beautiful. Another thing that struck me is the provincial flag of BC: the Union Jack at the top (OK, it is British Columbia), there are white and blue horizontal stripes, and [...]
So everybody is excited about the new GFAJ-1 bacterium that Felisa Wolfe-Simon and her colleagues have discovered. A common buzzphrase diffusing through the media and blogosphere is “NASA discovers a new life form“. (Or, better yet alien life.) Big press conference, and I just finished going through the article that Wolfe-Simon and colleagues have published in Science. Great [...]
If you entered this post to comment the error in the title, then I have one word for you. Gotcha! Yes, “warm blooded” animals are not, really, warm blooded. After all, a lizard in the baking sun has a core temperature higher than most mammals, but it is still called “cold blooded”. So-called cold blooded [...]
Yes, it’s that time when we all get together in front of the screen to watch another beautiful game played by that fantastic team contributing to the Carnival of Evolution. This time hosted on the lovely green pitch of Byte Size Biology. So get your popcorn, sunflower-seeds, crisps or any other culturally-appropriate sports-watching food and…… [...]
The 29th edition of the Carnival of Evolution will be hosted here. There are quite a few good things in store: on parrot feathers and lizardfish eyes, on Darwin cartoons, on dogs, dancing and much more. You can still contribute. So if you are a blogger with a post on evolution, go to the blog [...]
Sometimes I get the feeling that all life on Earth basically serves as a vehicle for viral replication and propagation. Viruses thrive in all three domains, they embed themselves in all creature’s genomes, they may lie dormant in the genome for eons or decimate whole populations in a few years, and they are the most [...]
I have written before about bacterial cooperation, and how cheating works, up to a point, in an environment of bacterial cooperation. That post talked about bacterial quorum sensing, the collective signaling mechanism by which bacteria construct supra-cellular structures called biofilms. Biofilms are tough multicellular enclosures that allow bacteria to survive and thrive in hostile environments, [...]
Some headlines just write themselves… It has been known for some time that an approaching large herbivore causes aphids to abandon ship …err plant. Makes sense since, after all, there’s not much of a point in staying on the particular bit of shrubbery that will be consumed, lock, stalk and barrel by a ravenous forager. [...]
