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Science

Short note on getting students busy

I recently read this post about lacunae in  Bioinformatics.  One complaint was: I know that documentation is a thankless task. But some parts of the Bio[Java|Perl|Python] libraries are described only as an API? This became apparent to me when I had to teach the libraries to students. What does this module do and why does it do […]

Should research code be released as part of the peer review process?

So there have been a few reactions to my latest post on accountable research software, including a Tweeter kerfuffle (again). Ever notice how people come out really aggressive on Twitter? Must the the necessity to compress ideas into 140chars. You can’t just write “Interesting point you make there, sir. Don’t you think that your laudable goal would […]

Can we make accountable research software?

Preamble: this post is inspired by a series of tweets that took place over the past couple of days. I am indebted to Luis Pedro Coelho (@LuisPedroCoelho) and to Robert Buels (@rbuels) for a stimulating, 140-char-at-a-time discussion. Finally, my thanks (and yours, hopefully) to Ben Temperton for initiating the Bioinformatics Testing Consortium. Science is messing around with […]

ZomBee Watch, a new citizen-scientist project

“If the bee disappeared off the surface of the globe, man would have only four years to live”. — Albert Einstein No, there are no typos in the title. And, no, there is no zombie outbreak towards which people are being recruited to fight. (Well, yeah, that’s what “they” always say isn’t it?)  The ZomBee Watch […]

Postdocs in Genome-Scale Proteomics, Imaging-based Screening and Cancer Biology

  Three postdocs positions available at a great lab in Denmark. Read on:   We are seeking three Postdoctoral Fellows to The Cellular Signal Integration Group (C-SIG). The group is a network biology research group located at the Department of Systems Biology at the Technical University of Denmark (DTU). Our department represents one of the […]

Taming the Impact Factor

Quite a bit has been written about how the journal impact factor (JIF) is a bad metric. The JIF is supposed to measure a journal’s impact using a formula that normalizes the number of cited articles in  a given time frame (typically a year). It is calculated exclusively by Thomson-Reuters, and is trademarked by this […]

ISMB 2012 Vignettes Pt. 3: Swag

Promotional materials are part of any conference. In scientific meetings, the swag usually comes from the booths of product promoters, science publishers, and scientific societies. It was a nice surprise to see a Federal funding agency, the US Department of Energy give away decks of cards. I’m a sucker for cards, so I took a […]

ISMB 2012 Vignettes Pt. 2: Phylogenomic Approaches to Function Prediction

I chaired the Automated Function Prediction meeting at ISMB this year. The meeting, held every year (almost) deals with the latest approaches to predicting protein function from genetic and genomic data, and also discussing the Critical Assessment of Function Annotation This year we were fortunate to have Jonathan Eisen as our keynote speaker. Ever wondered […]

ISMB 2012 Vignettes Pt. 1: Grant Writing Tips

ISMB 2012 was an excellent meeting. The organizers were celebrating the 20th anniversary of ISMB meetings, and have carefully chosen the keynote speakers to reflect not only the latest advances in bioinformatics, but also to talk about the past accomplishments,  how they led us to where were are now,  and what the future may hold.  […]

Spaghetti Western Blot

This is simply brilliant. The best thing since Bad Project.

Intermission: two vids

Too busy with grant deadlines, and preparations for the looming ISMB 2012. (Including, of course, the Automated Function Prediction meeting.) So here are two nice vids to pass the time. Jennifer Gardy and Tom Scott made this great A-Z of bacteria video.  Guaranteed to freak out your kids, or yourself. So how many of those […]

The Evolution of Music

A collaboration between a group in  Imperial College and Media Interaction group in Japan yielded a really cool website: darwintunes.org. The idea is to  apply Darwinian-like selection to music. Starting form a garble, after several generations producing  something that is actually melodic and listen-able. Or a Katy Perry tune. Whatever.  The selective force being the appeal of […]

Annotating Proteins in the Uncanny Valley

The Uncanny Valley Every day, software appears to do more things that we thought were exclusively in the human realm. Like beating a grandmaster in chess,  or carrying out a conversation. I say “appears” because there is obviously no self-aware intelligence involved, as this rather bizarre conversation between  Cleverbots demonstrates. For humans, playing chess  and carrying […]

Phound phage phootage

I am finishing up a great weekend at HHMI Janelia Farm Research Campus. The occasion is an annual symposium celebrating the Phage genomics Course taking place in dozens of universities in the USA. Here are two of our students, Erich Goebel and Morgan Light, next to the poster they presented at the meeting: This post […]

The Transit and Decline of Venus

From this: To this: