“We seek to download from the amazing successes of the computer industry two principles: that of open source, and that of crowdsourcing; to quickly, responsibly accelerate the delivery of targeted therapeutics to cancer patients. Our business model involves all of you. This research is funded by the public.”
Percent of pancreatic cancer patients diagnosed when the disease is still localized: 8 Their 5-year relative survival: 21.5% Percent of pancreatic cancer patients diagnosed when the disease has metastasized: 53 Their 5-year relative survival: 1.8% Mean survival rate after diagnosis: < 1 year Ranking in cause of cancer-related deaths worldwide: 4 Number of effective [...]
The central dogma of molecular biology edit: the sequence hypothesis (thanks for setting me straight, Kamel!) as formulated 57 years ago was simple: DNA is transcribed to mRNA,and mRNA is translated to proteins. Proteins are the business end of this process. mRNA is only the messenger: its sole function is to deliver information from the [...]
Recently, a judge in Federal District Court in Manhattan ruled that Myriad’s patents on BRCA1 and BRCA2 genes were invalid, being a “products of the law nature” and could be patented no more than, say, mount Everest. These two genes are associated with breast and ovarian cancer, and are used in testing for susceptibility to [...]
We learned in high school and/or undergrad biology that one antibody would bind to one antigen. This is what makes our immune system so effective: antibodies bind with high affinity to foreign proteins or other molecules. Not only that, but those antibodies are specific: they would bind only to a specific site on the foreign [...]
