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Structural biology

Da Vinci, F0-F1 ATPase: a copyright-driven Update

Harvard University has removed from YouTube the video I embedded  in my Leonardo Da Vinci and the F0-F1 ATPase post, due to copyright concerns. It is a pity. I believe the main sufferer from this step is the lab that actually created this video, and now has one outlet less to publicize its work. One […]

Leonardo Da Vinci and the F0-F1 ATPase

Offspring #2 (O2) and I  spent last weekend visiting the Da Vinci Experience exhibit at San Diego’s Air & Space Museum. The exhibit is engineer’s heaven: large wood models based on and inspired by LDV’s drawings. Gears, crankshafts, pulleys. O2 was interested in the military stuff:  catapults, the tank , a mobile bridge. I did […]

Ribosomal paleontology

In the latter epoch of those  2 billion-odd years between non-life and life on early Earth, our ancestral molecular replicators were quite probably RNA, not DNA. There are many arguments for this RNA world hypothesis: RNA can store information in its sequence, and self -duplicate; it can also catalyze reactions as a ribozyme. So technically, […]

Multitasking Antibody

We learned in high school and/or undergrad biology that one antibody would bind to one antigen. This is what makes our immune system so effective: antibodies bind with high affinity to foreign proteins or other molecules. Not only that, but those antibodies are specific: they would bind only to a specific site on the foreign […]