Displaying posts tagged with

“drug resistance”

The polypharmacome

Pharmaceutical companies are always on the lookout for secondary drug targets. After all, if you invest billions developing a single drug, you would be more than happy to sell it as a treatment for two, three, or more different ailments. Sildenafil citrate was developed to treat angina and hypertension, but during phase I clinical trials, […]

The Craigslist of Antibiotic Resistance

(Before we get going: this the the 100th post on Byte Size Biology. Happy Birthday to me!) Resistance to antibiotics is a huge clinical problem. In the US, more people die of  methicillin-resistant Staphylococcus aureus (MRSA) infections (nearly 19,000 in 2006) than of AIDS (14,627).  We know that antibiotic resistance is carried on mobile genetic […]