Pharmaceutical companies are always on the lookout for secondary drug targets. After all, if you invest billions developing a single drug, you would be more than happy to sell it as a treatment for two, three, or more different ailments. Sildenafil citrate was developed to treat angina and hypertension, but during phase I clinical trials, […]
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The polypharmacome
By Iddo on January 23rd, 2010
The Craigslist of Antibiotic Resistance
By Iddo on September 6th, 2009
(Before we get going: this the the 100th post on Byte Size Biology. Happy Birthday to me!) Resistance to antibiotics is a huge clinical problem. In the US, more people die of methicillin-resistant Staphylococcus aureus (MRSA) infections (nearly 19,000 in 2006) than of AIDS (14,627). We know that antibiotic resistance is carried on mobile genetic […]