Displaying posts tagged with

“genome annotation”

Gene and protein annotation: it’s worse than you thought

Sequencing centers keep pumping large amounts of sequence data into the omics-sphere (will I get a New Worst omics Word Award for this?)  There is no way we can annotate even a small fraction of those experimentally and indeed most  annotations are automatic, done bioinformatically. Typically function is inferred by homology: if the protein sequence [...]

The Human Genome Variome Project and Google News Reader

Apparently sequencing two white males of European extraction does not make for a very good sample of mankind, and that if we really want to get a good view of what we are really like, we need to sequence a couple more. Maybe even, you know, a woman, or someone from India or China or [...]

My own post genomic moment

Maybe I am slow on the uptake, but I never quite liked the term “post genomic”, and I used it very sparingly. (Yes, I do have that term in one of my better cited papers, smack in the first sentence of the abstract, but I never liked that).  Perhaps because of all the associated abuse [...]