Can we learn about an environment by looking at the bacteria living in it? Can we sequence a metagenome, and then say: ”according to the active genes in this water sample it appears to be too rich in metal ions / sewage products / other pollutants” ? In the foreseeable future could we sequence a [...]
Happy Darwin Day! If you are reading this then you probably do not need an introduction to Charles Darwin, the importance of his work, how his theory of evolution by natural selection shaped modern Biology. Or if you do, I bet there are plenty of posts in today’s blogswarm that will address this. There is [...]
A new documentary film follows life in a molecular biology lab in Columbia University over the course of three years. It looks very promising: the title is certainly something many of us identify with.
In any data-rich science, data visualization is of prime importance. Finding ways to visually depict data is challenging, as we have opposing demands: we would like to see the data in the whole, but also be able to zoom in and analyze the details; we would like to know how the many details add up [...]
Gradualism is a cornerstone principle in evolution. Things happen in small increments; all the time that changes happen, overall organism fitness cannot be compromised. So how then do full-featured complex functions appear? One way is by functional re-purposing of an existing organ: …an organ may become rudimentary for its proper purpose, and be used for [...]
Maybe I am slow on the uptake, but I never quite liked the term “post genomic”, and I used it very sparingly. (Yes, I do have that term in one of my better cited papers, smack in the first sentence of the abstract, but I never liked that). Perhaps because of all the associated abuse [...]
Here is a little trick I performed as a first year grad student a while ago and which I would like to share. My PhD adviser, Hanah Margalit was supposed to give a talk at a joint Israeli-Palestinian meeting. (Hopefully, such days will be back soon and permanently!) The audience was rather broad, and included [...]
I just went to Shirley Wu’s blog and found this. Apparently February 12-15, 2009 there will be a Blog for Darwin blogswarm, in honor of his 200th birthday and 150th anniversary of the publication of On the Origin of Species (First time I hear this term, blogswarm; not sure if I like it). I wrote [...]
(Continued from “On Microbial Sequencing“). Well, it’s really been a great meeting. The biology of pathogens, parasites and symbionts is amazing. Historically, the microbes that chiefly interested us were one of those three: those that causes disease in humans, animals (focus on domesticated animals), plants (again, mostly domesticated). However, as we are (alas, too slowly) [...]
A friend of mine who is also a scientist once told me: “the only time I read, is when I write”. What he meant was, that the only time he reads scientific literature, is when he writes his own papers, and needs to do the proper research to place his research in the context of [...]
